Glycogenolysis

I am real bird and welcome to my channel jeans pharmacy tutorials and today we are going to study about like or generalizes now let us have a look on the key points of glycogenolysis glycogenolysis means the breakdown of glycogen into glucose I repeat it is the breakdown of glycogen into glucose in other words the degradation of stored glycogen in liver and muscle constitutes glycogenolysis this whole process of glycogenolysis occurs in cytosol now let us have a look on the cycle of glycogen eliza's so first of all glycogen which is the starting material of glycogenolysis constitutes of 18 molecules of glucose which are branched the glucose which are connected in a chain are connected by alpha 1-4 glycosidic bond but the bond form that the branch unshin are connected by or linked by alpha 1-6 glycosidic bond now glycogen in the presence of the enzyme glycogen phosphorylase gets converted into glucose 1-phosphate this enzyme works until four residues of glucose are left on the either side four residues of glucose when left on the either side forms nimitz Textron limit dextran which is formed now cannot be further degraded where phosphorylase hence the branches of glycogen are cleaved by debranching enzyme now first of all in the debranching enzyme the fragment of glucose molecule which contains 3 molecules of glucose is transferred to another chain this ohhere debranching enzyme shows transferase activity now the resulting glycogen molecules from under the action of debranching enzyme will am i low alpha one six glucose a days great the alpha one six bonds and a single glucose molecule is released now the remaining molecular glycogen is again available for the action of phosphorylase and gets converted into glucose 1-phosphate now glucose 1-phosphate in the presence of the enzyme phosphoglucomutase gets converted into glucose 6-phosphate this leukocytes phosphate is further utilized in the glycolysis process but in believers glucose 6-phosphate under the presence of the enzyme glucose-6-phosphatase gets converted into glucose

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